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A small step towards meaningful change
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What is IQOS?
What is IQOS?
An alternative to smoking
All tobacco heating devices
Discover the science
A small step towards meaningful change
Alternative to cigarettes
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Care you can count on
Care and privileges
Free expert IQOS ILUMA maintenance
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The science and the research behind IQOS.
Our scientific assessment journey.
Scientific programme.
We have developed a comprehensive step-by-step scientific assessment programme. This programme is inspired by the practices of the pharmaceutical industry and is in line with the USA’s Federal Drug Administration’s 2012 guidance on the assessment of candidate Modified Risk Tobacco products. Our assessment was also conducted according to international standards.
Is IQOS less toxic?
In laboratory settings, we found that IQOS’ tobacco vapour is less toxic than cigarette smoke. Our scientists test our products thoroughly before they go into adult smokers’ hands. Using in vitro assays in our labs, we assessed the cytotoxicity and genotoxicity of IQOS tobacco vapor in comparison with the smoke of a reference cigarette designed for research purposes. Taken together, the results of these assays show that IQOS tobacco vapour is significantly less toxic than the smoke from reference cigarette.
This is just a glimpse of our work. These tests were crucial before we moved on to test IQOS with thousands of adult smokers who voluntarily participated in our clinical study programme and ultimately allowed us to commercialize our products.
Clinical studies.
Do the significantly lower number and levels of harmful chemicals in IQOS tobacco vapour also mean lower levels of such chemicals in the body? If you reduce the level of harmful chemicals in IQOS tobacco vapour, it would make sense that switching completely to IQOS from cigarettes reduces exposure to these harmful chemicals. To prove this, we measured biomarkers of exposure for a number of these harmful chemicals in thousands of smokers who participated in our clinical study programme (some switched to IQOS, while others either continued smoking their cigarette brand or quit for the duration of the study).
These studies show that when smokers switch to IQOS, their body absorbs significantly lower levels of harmful chemicals, which in turn results in favorable changes in a number of risk markers selected because of their known association with smoking-related diseases. But it doesn't end there.
Using IQOS device
Based on all the scientific evidence, we are confident that switching completely to IQOS is less harmful than continuing to smoke.*
However, and this is important: IQOS is not risk-free, it delivers nicotine which is addictive.
The absolute best choice remains to quit tobacco and nicotine use altogether. IQOS is not an alternative to cessation.
* Based on the totality of evidence available for IQOS in comparison with continuing to smoke.
Long term studies.
Once IQOS is available in the market, the research moves from being conducted in a pre-market setting to a real-world post-market setting. There, we look at how the product is being used and by whom in order to complement our pre-market findings and to do our best to identify and prevent use or uptake by unintended audiences. After years of commercialization in many countries, the available data confirms our pre-market observations, in particular in terms of IQOS’ appeal to adult smokers and the relative lack of interest in former and never smokers.
We also monitor reports of health effects now that the product is used by millions of adult users. Long-term studies will eventually help us to evaluate the potential disease–specific risk reduction of IQOS. Gathering data to answer this question takes time, but it’s the right choice. So far, all the data we’ve seen points in the right direction.
The result.
IQOS is a better choice than continued smoking. Switching completely to IQOS presents less risk to your health than continuing to smoke.*
Important information: IQOS is not risk-free and provides nicotine, which is addictive.
* Based on the totality of evidence available for IQOS in comparison with continuing to smoke.